Neuroprotective effect of pretreatment with Lavandula officinalis ethanolic extract on blood-brain barrier permeability in a rat stroke model
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چکیده
منابع مشابه
Relationship between dietary virgin Olive oil on brain Cholesterol, Cholesteryl ester and Triglyceride levels and Blood Brain Barrier (BBB) permeability in a rat stroke model
Introduction: Recent studies suggest that dietary virgin olive oil (VOO) reduces hypoxia-re oxygenation injury in rat brain. We have attempted to determine the effect of dietary virgin olive oil on brain lipidomics and its relationship with brain edema in a rat stroke model. Methods: Five groups, each consisting of 6 male Wistar rats, were studied. The first and second groups (control and s...
متن کاملEffect of Dietary Ethanolic Extract of Lavandula officinalis on Serum Lipids Profile in Rats
Antioxidants are effective in prevention and treatment of cardiovascular diseases. Lavandula officinalis possesses antioxidant activity, therefore, in this study; the effects of Lavandula officinalis extract were investigated on serum lipids levels of rats. Experimental mature male Wistar rats were treated with 100, 200 or 400 mg/Kg/day of lavender ethanolic extract or distilled water for 25 da...
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abstract ischemic brain edema is one of the most important complications of a stroke. this study aims to investigate the impact of pre-feeding of flax seed oil on blood-brain barrier in rat stroke model. in this experimental study animals were randomly divided into 3 groups of experiment, sham, and control. each testing group itself was consisted of 3 subgroups receiving doses of flaxseed oil w...
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Recent studies have suggested that Mentha longifolia L. extracts (ME) have anti-inflammatory and antioxidant activities. In this paper, we attempted to determine the effect of ME in a rat stroke model. Five groups of experimental animals were used (n=14); the first and second groups (control and sham, respectively) received intraperitoneal injections of daily-distilled water; the other three gr...
متن کاملQuantitative evaluation of Blood Brain Barrier permeability in transient focal cerebral ischemia in the rat
Introduction: Development of brain edema following focal cerebral ischemia exacerbates primary ischemic injury. Blood brain barrier (BBB) opening is an important part of edema named as vasogenic brain edema. In this study, quantitative alterations of BBB permeability is experimentally evaluated using transient focal cerebral ischemia in the rat. Methods: Two groups of male rats (ischemic and sh...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Tropical Medicine
سال: 2014
ISSN: 1995-7645
DOI: 10.1016/s1995-7645(14)60269-8